中文名称 | 3-(1-((3,3-二苯丙基)(甲基)氨基)-2-甲基丙-2-基) 5-甲基 2,6-二甲基-4-(3-硝基苯基)-1,4-二氢吡啶-3,5-二羧酸酯盐酸盐;盐酸乐卡地平 |
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英文名称 | Lercanidipine hydrochloride |
CAS号 | 132866-11-6 |
分子式 | C36H42ClN3O6 |
分子量 | 648.19 |
MDL | MFCD07773089 |
外观 | Light yellow to yellow powder |
储存条件 | 4°C, sealed storage, away from moisture |
Lercanidipine, a third-generation dihydropyridine calcium channel blocker, exhibits a pIC50 of 7.74 and features lipophilicity, brain penetration, and vascular selectivity . It demonstrates sustained antihypertensive effects, along with reno- and neuroprotection, and possesses antioxidant, anti-inflammatory, and anti-apoptotic properties, making it relevant for cardiovascular and neurological research.
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