依那妥组单抗
Enavatuzumab (Anti-TNFRSF12A / TWEAKR / CD266)
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1 mg 5 mg 10 mg 50 mg
产品库存
3-5days
目录价格
¥4000.00
会员价格
产品库存
3-5days
目录价格
¥16600.00
会员价格
产品库存
3-5days
目录价格
¥28500.00
会员价格
产品库存
3-5days
目录价格
¥127500.00
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- +
基本信息
中文名称依那妥组单抗
英文名称 Enavatuzumab (Anti-TNFRSF12A / TWEAKR / CD266)
CAS号1062149-33-0
储存条件Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage. Use a manual defrost freezer and avoid repeated freeze-thaw cycles, away from light.
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产品详情

Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK) . TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab can actively recruits and activates myeloid effectors to kill tumor cells. Enavatuzumab inhibits the growth of various human TweakR-positive cancer cell lines and xenografts in vitro and in vivo.

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依那妥组单抗
N-苄氧羰基-L-alpha-天冬氨酰-L-alpha-谷氨酰-N-[(1S)-3-氟-1-(2-甲氧基-2-氧代乙基)-2-氧代丙基]-L-缬氨酰胺 1,2-二甲酯