法瑞西单抗
Anti-Human VEGFAxANGPT2 (Faricimab; RG7716)
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中文名称法瑞西单抗
英文名称 Anti-Human VEGFAxANGPT2 (Faricimab; RG7716)
CAS号1607793-29-2
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Faricimab is a pioneering humanized bispecific antibody that targets both VEGF-A and Ang-2, offering a dual inhibition approach for retinal diseases like DME and nAMD. By inhibiting VEGF-A, it reduces endothelial cell proliferation and vascular permeability, while blocking Ang-2 is believed to enhance vascular stability and counteract VEGF-A effects. Faricimab has demonstrated a significant reduction in annual injections compared to other anti-VEGF treatments, with a comparable efficacy and safety profile, positioning it as a valuable treatment option for patients with retinal diseases.


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