中文名称 | 埃万妥单抗 |
---|---|
英文名称 | Anti-Human EGFRxMET Bispecific Antibody(Amivantamab; JNJ-61186372) |
CAS号 | 2171511-58-1 |
储存条件 | -20°C for 3 years | In solvent: -80°C for 1 year |
Amivantamab (JNJ-61186372) is a fully human EGFR-MET bispecific antibody that combats resistance in NSCLC through multifaceted mechanisms: ligand blockade, receptor degradation, and immune cell activation, including ADCC and trogocytosis. This innovative approach targets both primary and acquired resistance, offering a new therapeutic avenue for patients with EGFR and MET aberrations.
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