中文名称 | (S)-N-[[3-(3'-氟-4'-吗啉基苯基)-2-氧代-5-噁唑烷基]甲基]邻苯二甲酰亚胺 |
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英文名称 | Deacetamide Linezolid Phthalimide; (S)-N-[[3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide |
CAS号 | 168828-89-5 |
分子式 | C22H20FN3O5 |
分子量 | 425.41 |
MDL | MFCD18382488 |
外观 | White crystalline powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Deacetamide Linezolid Phthalimide (CAS: 168828-89-5) is a pivotal intermediate in the synthesis of Linezolid, an antibiotic that uniquely targets the 50S ribosomal subunit to inhibit bacterial protein synthesis. This compound plays a critical role in developing new antimicrobials to combat the rise of antibiotic resistance. Its bioactivity is highlighted by its effectiveness against Gram-positive bacteria, including MRSA and VRE. As per ICH guidelines, it is also crucial for monitoring impurity levels in Linezolid formulations, ensuring both efficacy and safety in clinical use.
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