中文名称 | 瑞他鲁肽 |
---|---|
英文名称 | Retatrutide | LY3437943 |
CAS号 | 2381089-83-2 |
分子式 | C221H342N46O68 |
分子量 | 4731.33 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at -20 ℃ for 1 year or -80 ℃ for 2 years |
Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity.
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