5-氨基酮戊酸己酯盐酸盐
Hexaminolevulinate Hydrochloride (Synonyms: Hexyl 5-aminolevulinate hydrochloride; P-1206; 5-Aminolevulinic acid hexyl ester Hydrochloride)
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基本信息
中文名称5-氨基酮戊酸己酯盐酸盐
英文名称 Hexaminolevulinate Hydrochloride (Synonyms: Hexyl 5-aminolevulinate hydrochloride; P-1206; 5-Aminolevulinic acid hexyl ester Hydrochloride)
CAS号140898-91-5
分子式C11H22ClNO3
分子量251.75
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Hexaminolevulinate hydrochloride, also known as hexyl 5-aminolevulinate HCl, is the hexyl ester of 5-aminolevulinic acid (ALA) with photodynamic properties. As a precursor of photoactive porphorins, hexyl 5-aminolevulinate induces the endogenous production of the photosensitizer protoporphyrin IX (PPIX) which accumulates selectively in tumor tissue. When exposed to specific wavelengths of light, PPIX is activated and, depending on the wavelength and/or intensity of light, either fluoresces, thereby allowing tumor imaging, or induces tumor cell apoptosis.
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