中文名称 | 5-氨基酮戊酸己酯盐酸盐 |
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英文名称 | 5-Aminolevulinic acid hexyl ester Hydrochloride; Hexaminolevulinate Hydrochloride |
CAS号 | 140898-91-5 |
分子式 | C11H22ClNO3 |
分子量 | 251.75 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Hexaminolevulinate hydrochloride, also known as hexyl 5-aminolevulinate HCl, is the hexyl ester of 5-aminolevulinic acid (ALA) with photodynamic properties. As a precursor of photoactive porphorins, hexyl 5-aminolevulinate induces the endogenous production of the photosensitizer protoporphyrin IX (PPIX) which accumulates selectively in tumor tissue. When exposed to specific wavelengths of light, PPIX is activated and, depending on the wavelength and/or intensity of light, either fluoresces, thereby allowing tumor imaging, or induces tumor cell apoptosis.
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