中文名称 | 贯叶金丝桃素 二环己基铵盐 | 贯叶金丝桃素-DCHA |
---|---|
英文名称 | Hyperforin dicyclohexylammonium salt/Hyperforin-DCHA(Hyp-DCHA) |
CAS号 | 238074-03-8 |
分子式 | C35H52O4·C12H23N |
分子量 | 718.10 |
外观 | White to light yellow powder |
储存条件 | 4°C, sealed storage, away from moisture |
Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channel activator. Hyperforin dicyclohexylammonium salt regulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt also displays a variety of bioactivities like antidepressant, antitumor, antidementia, and antidiabetic activities. Hyperforin dicyclohexylammonium salt regulates the secretion of IL-17α from γδ T cells and improves Imiquimod induced skin inflammation in psoriasis-like mice.
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