佛司可林; 弗斯可林; 毛喉素
Forskolin (Synonyms: Coleonol;Colforsin;HL 362)
Herbleader
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基本信息
中文名称佛司可林; 弗斯可林; 毛喉素
英文名称 Forskolin (Synonyms: Coleonol;Colforsin;HL 362)
CAS号66575-29-9
分子式C22H34O7
分子量410.5
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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1. Forskolin (Colforsin) is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology. Forskolin also activates PXR and FXR activity. Forskolin stimulates autophagy
2. Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy.

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佛司可林; 弗斯可林; 毛喉素