| 中文名称 | 京尼平 |
|---|---|
| 英文名称 | Genipin (Synonyms: (+)-Genipin) |
| CAS号 | 6902-77-8 |
| 分子式 | C11H14O5 |
| 分子量 | 226.23 |
| 外观 | White crystalline powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Genipin((+)-Genipin) is an active aglycone derived from an iridoid glycoside called geniposide, which is found in the fruit of Gardenia jasminoides Ellis. Genipin was originally identified as a protein cross-linking agent. Genipin ameliorates hypertension-induced renal damage via the angiotensin II-TLR/MyD88/MAPK pathway. genipin shows therapeutic potential for central neurodegenerative diseases. IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma.
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