中文名称 | 7-乙基-10-羟基喜树碱 | SN-38 |
---|---|
英文名称 | 7-Ethyl-10-hydroxycamptothecin | SN-38 | NK012 |
CAS号 | 86639-52-3 |
分子式 | C22H20N2O5 |
分子量 | 392.40 |
MDL | MFCD00871873 |
外观 | Light yellow crystalline powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
SN-38 (NK012) is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. SN-38 induces autophagy.
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