中文名称 | 紫杉醇 |
---|---|
英文名称 | Paclitaxel | NSC 125973 | PTX |
CAS号 | 33069-62-4 |
分子式 | C47H51NO14 |
分子量 | 853.91 |
外观 | White crystalline powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Paclitaxel is a compound with antineoplastic activity extracted from the Pacific yew tree Taxus brevifolia. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby inhibiting cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2).
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