中文名称 | (2S,3R,4S,5S,6R)-2-(((2S,3R,4S,5S,6R)-4,5-二羟基-2-(((3R,6R)-2-羟基-6-((3S,8S,9R,10R,11R,13R,14S,17R)-11-羟基-4,4,9,13,14-五甲基-3-(((2R,3R,4S,5S,6R)-3,4,5-三羟基-6-((((2R,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)甲基)四氢-2H-吡喃-2-基)氧基)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-十四氢-1H-环戊[a]菲-17-基)-2-甲基庚-3-基)氧基)-6-((((2R,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-yl)氧基)甲基)四氢-2H-吡喃-3-基)氧基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇; 罗汉果苷V; 罗汉果甜苷V; 罗汉果皂苷V |
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英文名称 | Mogroside V |
CAS号 | 88901-36-4 |
分子式 | C60H102O29 |
分子量 | 1,287.43 |
MDL | MFCD00238649 |
外观 | White to off-white powder |
储存条件 | 4°C, protect from light |
Mogroside V, a key active component in Siraitiae Fructus, is a potent non-sugar sweetener with an in vitro AMPK-activating effect. It demonstrates anti-inflammatory properties in murine macrophages and a murine ear edema model, and it may protect against LPS-induced airway inflammation in acute lung injury (ALI) models. This triterpenoid glycoside also possesses antioxidant capabilities, mitigates intracellular reactive oxygen species (ROS) levels, and enhances mitochondrial function. Mogroside V exhibits anti-oxidative, anti-diabetic, and anti-carcinogenic effects, making it a valuable compound for diabetes research. It is particularly relevant for pancreatic cancer models, where it inhibits tumor growth.
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