中文名称 | 异紫堇定碱; 右旋异紫堇定 |
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英文名称 | (+)-Isocorynoline (Synonyms: Isocorydine) |
CAS号 | 475-67-2 |
分子式 | C20H23NO4 |
分子量 | 341.40 |
Isocorynoxeine, a major bioactive tetracyclic oxindole alkaloids found in Uncaria rhynchophylla, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM and shows various beneficial effects, including lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage.
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