中文名称 | 芥芬胺; 蒜黎芦碱 |
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英文名称 | Jervine (Synonyms: 11-Ketocyclopamine) |
CAS号 | 469-59-0 |
分子式 | C27H39NO3 |
分子量 | 425.60 |
Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC50 of 500-700 nM. Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties.
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