中文名称 | 珊塔玛内酯 | 裂叶苣荚莱内酯 |
---|---|
英文名称 | Santamarine | Balchanin | Santamarin |
CAS号 | 4290-13-5 |
分子式 | C15H20O4 |
分子量 | 264.32 |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Santamarine (Santamarin), a sesquiterpene lactone, increases HO-1 expression through Nrf2 translocation and suppresses NO, PGE2, TNF-α, and IL-1β production through inhibition of NF-κB translocation in LPS-induced macrophages. Santamarine shows anti-photoaging properties via inhibition of MAPK/AP-1 and stimulation of TGF-β/Smad signaling in UVA-irradiated human dermal fibroblasts (HDFs). Antioxidant activities.
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