中文名称 | 半枝莲碱A |
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英文名称 | Scutebarbatine A |
CAS号 | 176520-13-1 |
分子式 | C32H34N2O7 |
分子量 | 558.62 |
外观 | White to off-white powder |
储存条件 | 20°C, protect from light |
Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspase-3 and 9, and down-regulating Bcl-2. Scutebarbatine A and barbatine A show a significant ability to protect cells against H2O2 with ED50 values of 5.0 and 16.8 uM, respectively.
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