Sibiricin | (S)-8-[(3,3-二甲基环氧乙烷基)甲基]-5,7-二甲氧基-2H-1-苯并吡喃-2-酮
Sibiricin
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中文名称Sibiricin | (S)-8-[(3,3-二甲基环氧乙烷基)甲基]-5,7-二甲氧基-2H-1-苯并吡喃-2-酮
英文名称 Sibiricin
CAS号95188-34-4
分子式C16H18O5
分子量290.31
储存条件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Sibiricin is a natural indole alkaloid that has been isolated from the roots of S. sibericum, an evergreen plant native to Siberia. It is a phebalosin analog and has shown in vivo activity against intestinal bacteria, such as Salmonella enterica and Escherichia coli, in mice. Sibiricin also inhibits fatty acid synthesis and has been shown to have anti-inflammatory effects in vitro. Magnetic resonance spectroscopy has shown that sibiricin increases the metabolic rate of human liver cells by affecting mitochondrial function. The antibiotic can be used as a vaccine adjuvant for diseases with bacterial origins, such as tuberculosis.


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