中文名称 | 毛果一枝黄花皂苷元G | 远志酸 |
---|---|
英文名称 | Virgaureagenin G | Polygalacic acid |
CAS号 | 22338-71-2 |
分子式 | C30H48O6 |
分子量 | 504.71 |
外观 | White to off-white powder |
储存条件 | 4°C, protect from light |
Polygalacic acid (Virgaureagenin G) is a triterpenoid isolated from the root of Polygala tenuifolia Willd that inhibits MMP expression. Polygalacic acid (Virgaureagenin G) can significantly improve the responsiveness of the cholinergic system, such as decreased acetylcholinesterase (AChE) activity, increased choline acetyltransferase (ChAT) activity, and increased acetylcholine (ACh) levels in the hippocampus and frontal cortex. Polygalacic acid (Virgaureagenin G) can also inhibit IL-1β-induced Wnt/β-catenin activation and mitogen-activated protein kinase (MAPK) signaling pathways in chondrocytes, and is used in osteoarthritis (OA) related research.
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