Ercalcitriol; 1α, 25-Dihydroxyvitamin D2

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基本信息

英文名称	Ercalcitriol; 1α, 25-Dihydroxyvitamin D2
中文名称	1α,25-二羟基维生素 D2
CAS号	60133-18-8
分子式	C28H44O3
分子量	428.65
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

产品详情

Ercalcitriol, also known as RO-17-6218 or 1,25-dihydroxyvitamin D2, is the active circulating metabolite of vitamin D2 formed by 25-hydroxylase in the liver and 25-hydroxyvitamin D-hydroxylase in the kidney. By binding to the vitamin D receptor (VDR), 1,25-dihydroxy Vitamin D2 activates VDR to interact with the retinoid X receptor (RXR), forming the VDR/RXR/cofactor complex, which regulates gene transcription.

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