Posaconazole (SCH 56592)

规格	库存	目录价	会员专享价	数量
10 mg	3-5days	￥450.00	登录后可见	- +
25 mg	3-5days	￥650.00	登录后可见	- +
50 mg	3-5days	￥950.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

10 mg

3-5days

￥450.00

登录后可见

- +

25 mg

3-5days

￥650.00

登录后可见

- +

50 mg

3-5days

￥950.00

登录后可见

- +

基本信息

英文名称	Posaconazole (SCH 56592)
中文名称	泊沙康唑
CAS号	171228-49-2
分子式	C37H42F2N8O4
分子量	700.78
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Posaconazole (also known as SCH 56592 or trade name of Noxafil) is a potent,broad-spectrum, second generation triazole antifungal compound that potently inhibits 14α-demethylation in a variety of fungi, including Candida and Aspergillus, with half maximal inhibition concentration IC50 of 0.007 μg/ml, 0.06 μg/ml, 0.2 μg/ml, 0.3 μg/ml, 0.03 μg/ml and 0.03 μg/ml respectively Posaconzole, an itraconzole derivative with fluorine replacing chlorine in the phenyl ring and hydroxylation in the side chain, binds to the heme cofactor on the active site of 14α-demethylase, which converts lanosterol to 14α-dimethy lanosterol, resulting in the disruption of the integrity and function of the fungal cell membrane and inhibition of fungal growth.

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CL2521

泊沙康唑

171228-49-2 98+% 3-5days

￥450.00 10 mg