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阿迪普隆

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AdipoRon

产品编号：CL2528 CAS No.：924416-43-3 MDLNo： 分子式：C27H28N2O3 分子量：428.52

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规格	库存	目录价	会员专享价	数量
10 mg	3-5days	￥480.00	登录后可见	- +
25 mg	3-5days	￥720.00	登录后可见	- +
50 mg	3-5days	￥1350.00	登录后可见	- +

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基本信息

英文名称	AdipoRon
中文名称	阿迪普隆
CAS号	924416-43-3
分子式	C27H28N2O3
分子量	428.52
外观	Off-white to light yellow powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

AdipoRon (also known as SC-396658) is a novel, first-in-class, and orally bioavailable adiponectin receptor agonist with KD of 1.8 and 3.1 μM for AdipoR1 and AdipoR2, respectively. AdipoRon (5-50 μM) increased AMPK phosphorylation via AdipoR1 in a dose-dependent way. Also, AdipoRon replenished adiponectin-stimulated AMPK phosphorylation. In C2C12 myotubes, AdipoRon increased PGC-1α expression and mitochondrial DNA content in a Ca2+- and dose-dependent way.