首页 > 产品目录 > 信号通路 > Endocrinology & Hormones > Estrogen/progestogen Receptor > (Z)-4-(1-[4-(二甲基氨基乙氧基)苯基]-2-苯基-1-丁烯)苯酚/4-羟基他莫昔芬

(Z)-4-(1-[4-(二甲基氨基乙氧基)苯基]-2-苯基-1-丁烯)苯酚/4-羟基他莫昔芬

ChemLeader 98+%

4-Hydroxytamoxifen;(Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen;(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol

产品编号:CL1009 CAS No.:68047-06-3 MDLNo: 分子式:C26H29NO2 分子量:387.52
规格 库存 目录价 会员专享价 数量
5 mg In-stock ¥300.00 登录后可见
- +
10 mg In-stock ¥550.00 登录后可见
- +
25 mg In-stock ¥1050.00 登录后可见
- +
50 mg In-stock ¥2000.00 登录后可见
- +

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

  • 基本信息
  • 相关文档
  • 产品详情
  • 相关文献
基本信息
英文名称 4-Hydroxytamoxifen;(Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen;(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol
中文名称(Z)-4-(1-[4-(二甲基氨基乙氧基)苯基]-2-苯基-1-丁烯)苯酚/4-羟基他莫昔芬
CAS号68047-06-3
分子式C26H29NO2
分子量387.52
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen. It is formed from tamoxifen by the cytochrome P450 (CYP) isoform CYP2D6. (E/Z)-4-hydroxy Tamoxifen is cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively). It also stimulates LC3 lipidation and the formation of autophagic vesicles in MCF-7 cells in a superoxide-dependent manner. 

相关文献
抱歉,暂时没有相关文献
在线客服
小德
021-58180488
小立
021-58180488
在线服务时间: 工作日 9:00-18:00