英文名称 | Amifostine Trihydrate | WR2721 trihydrate |
---|---|
中文名称 | 氨磷汀三水合物 |
CAS号 | 112901-68-5 |
分子式 | C5H21N2O6PS |
分子量 | 268.27 |
外观 | White crystal or crystalline powder |
储存条件 | 4°C, protect from light, stored under nitrogen |
英文名称 | Amifostine Trihydrate | WR2721 trihydrate |
---|---|
中文名称 | 氨磷汀三水合物 |
CAS号 | 112901-68-5 |
分子式 | C5H21N2O6PS |
分子量 | 268.27 |
外观 | White crystal or crystalline powder |
储存条件 | 4°C, protect from light, stored under nitrogen |
Amifostine trihydrate(WR2721 trihydrate) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.
PMID: 28392886 PMCID: PMC5368387 DOI: 10.1155/2017/4130824
Amifostine: the first selective-target and broad-spectrum radioprotector.
PMID: 17602063 DOI: 10.1634/theoncologist.12-6-738
Amifostine induces anaerobic metabolism and hypoxia-inducible factor 1 alpha.
PMID: 14574457 DOI: 10.1007/s00280-003-0691-z