英文名称 | Temoporfin (KW-2345; m-THPC) |
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中文名称 | 替莫泊芬,替莫卟吩; 2,3-二氢-5,10,15,20-四(间羟苯基)卟啉 |
CAS号 | 122341-38-2 |
分子式 | C44H32N4O4 |
分子量 | 680.75 |
外观 | Black purple powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名称 | Temoporfin (KW-2345; m-THPC) |
---|---|
中文名称 | 替莫泊芬,替莫卟吩; 2,3-二氢-5,10,15,20-四(间羟苯基)卟啉 |
CAS号 | 122341-38-2 |
分子式 | C44H32N4O4 |
分子量 | 680.75 |
外观 | Black purple powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Temoporfin is a synthetic chlorin with light-activated actions. When administered systemically, temoporfin accumulates in tumor cells , When stimulated with light (650-652 nm) in the presence of oxygen, reactive oxygen species are generated, leading to necrosis within the tumor. Different approaches to using photodynamic therapy with temoporfin in palliative care are currently of interest.