首页 > 产品目录 > 信号通路 > MAPK/ERK Pathway > MEK > N-[(2R)-2,3-二羟基丙氧基]-3,4-二氟-2-[(2-氟-4-碘苯)氨基]苯甲酰胺

N-[(2R)-2,3-二羟基丙氧基]-3,4-二氟-2-[(2-氟-4-碘苯)氨基]苯甲酰胺

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Mirdametinib (PD0325901)

产品编号:CL1077 CAS No.:391210-10-9 MDLNo: 分子式:C16H14F3IN2O4 分子量:482.19
规格 库存 目录价 会员专享价 数量
10 mg In-stock ¥200.00 登录后可见
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50 mg In-stock ¥680.00 登录后可见
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100 mg In-stock ¥1200.00 登录后可见
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基本信息
英文名称 Mirdametinib (PD0325901)
中文名称N-[(2R)-2,3-二羟基丙氧基]-3,4-二氟-2-[(2-氟-4-碘苯)氨基]苯甲酰胺
CAS号391210-10-9
分子式C16H14F3IN2O4
分子量482.19
外观White powder
储存条件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

Mirdametinib, also known as PD-0325901, is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors.

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