首页 > 产品目录 > 信号通路 > DNA Damage/DNA Repair > DNA/RNA Synthesis > AOH1996

AOH1996

ChemLeader Purity: 99.17%

AOH1996 | N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide

产品编号:CL1093 CAS No.:2089314-64-5 MDLNo: 分子式:C26H22N2O4 分子量:426.46
规格 库存 目录价 会员专享价 数量
5 mg In-stock ¥1000.00 登录后可见
- +
10 mg In-stock ¥1600.00 登录后可见
- +
25 mg In-stock ¥2800.00 登录后可见
- +

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

  • 基本信息
  • 相关文档
  • 产品详情
  • 相关文献
基本信息
英文名称 AOH1996 | N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide
中文名称AOH1996
CAS号2089314-64-5
分子式C26H22N2O4
分子量426.46
外观White powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

AOH1996 is an inhibitor of proliferating cell nuclear antigen (PCNA).It binds to PCNA in a thermal shift assay. AOH1996 (500 nM) induces apoptosis in SK-N-DZ neuroblastoma cells but not 7SMOO32 normal neural crest stem cells. It induces DNA damage in SK-N-AS neuroblastoma cells expressing wild-type DNA-directed RNA polymerase II subunit RPB1 but not in SK-N-AS cells expressing RPB1Y418A. AOH1996 (40 mg/kg) decreases tumor volume in SK-N-BE(2)-C neuroblastoma, MDA-MB-468 breast cancer, and NCI H82 small cell lung cancer mouse xenograft models.

相关文献
抱歉,暂时没有相关文献
相关产品
抱歉,暂时没有相关产品
在线客服
小德
021-58180488
小立
021-58180488
在线服务时间: 工作日 9:00-18:00