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碘苷; 5-碘-2'-脱氧尿苷

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Idoxuridine (5-IUdR,5-Iodo-2′-deoxyuridine); 5-I-2’-dU; 5-Iodo-2’-Deoxyuridine

产品编号:CL1198 CAS No.:54-42-2 MDLNo: 分子式:C9H11IN2O5 分子量:354.10
规格 库存 目录价 会员专享价 数量
500 mg 3-5days ¥150.00 登录后可见
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1 g 3-5days ¥220.00 登录后可见
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5 g 3-5days ¥600.00 登录后可见
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基本信息
英文名称 Idoxuridine (5-IUdR,5-Iodo-2′-deoxyuridine); 5-I-2’-dU; 5-Iodo-2’-Deoxyuridine
中文名称碘苷; 5-碘-2'-脱氧尿苷
CAS号54-42-2
分子式C9H11IN2O5
分子量354.10
外观White to off-white powder
储存条件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

Idoxuridine is an anti-herpesvirus antiviral and anticancer drug. It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. It is used only topically due to cardiotoxicity. It was synthesized by William Prusoff in the late 1950s. Initially developed as an anticancer drug, idoxuridine became the first antiviral agent in 1962.

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