英文名称 | Topotecan Hydrochloride;Topotecan HCl |
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中文名称 | 盐酸拓扑替康; 盐酸托泊替康 |
CAS号 | 119413-54-6 |
分子式 | C23H23N3O5.HCl |
分子量 | 457.91 |
外观 | Off-white to yellow powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名称 | Topotecan Hydrochloride;Topotecan HCl |
---|---|
中文名称 | 盐酸拓扑替康; 盐酸托泊替康 |
CAS号 | 119413-54-6 |
分子式 | C23H23N3O5.HCl |
分子量 | 457.91 |
外观 | Off-white to yellow powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Topotecan HCl is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. Topotecan HCl induces autophagy and apoptosis.