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奥希替尼 | 迈瑞替尼

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Osimertinib | Mereletinib | AZD-9291

产品编号:CL2211 CAS No.:1421373-65-0 MDLNo: 分子式:C28H33N7O2 分子量: 499.62
规格 库存 目录价 会员专享价 数量
250 mg In-stock ¥300.00 登录后可见
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1 g In-stock ¥850.00 登录后可见
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基本信息
英文名称 Osimertinib | Mereletinib | AZD-9291
中文名称奥希替尼 | 迈瑞替尼
CAS号1421373-65-0
分子式C28H33N7O2
分子量 499.62
外观Off-white powder
储存条件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

Osimertinib, also known as AZD-9291 and Mereletinib, is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. It inhibits both activating and resistant EGFR mutations while sparing the normal form of EGFR that is present in normal skin and gut cells, thereby reducing the side effects encountered with currently available medicines. Osimertinib was approved in Nov. 2015 by FDA.

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