Navitoclax (ABT-263)

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规格

库存

目录价

会员专享价

数量

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基本信息

英文名称	Navitoclax (ABT-263)
中文名称	Navitoclax (ABT-263)
CAS号	923564-51-6
分子式	C47H55ClF3N5O6S3
分子量	974.61
外观	White to light yellow powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Navitoclax, also known as ABT-263, is an orally bioavailable, synthetic small-molecule antagonist of a subset of the B-cell leukemia 2 (Bcl-2) family of proteins with potential antineoplastic activity. ABT-263 selectively binds to apoptosis suppressor proteins Bcl-2, Bcl-XL, and Bcl-w and prevents their binding to the apoptotic effectors Bax and Bak proteins, which may trigger apoptosis in tumor cells overexpressing Bcl-2, Bcl-XL, and Bcl-w.

Navitoclax (ABT-263)

Navitoclax (ABT-263)

化学品安全说明书(MSDS)

质检证书(COA)