Oclacitinib Maleate (PF-03394197 Maleate

规格	库存	目录价	会员专享价	数量
暂无牌价信息，您可以发送询价，我们会尽快给你回复。

规格

库存

目录价

会员专享价

数量

暂无牌价信息，您可以发送询价，我们会尽快给你回复。

基本信息

英文名称	Oclacitinib Maleate (PF-03394197 Maleate)
中文名称	奥拉替尼马来酸盐 (1208319-27-0)
CAS号	1640292-55-2
分子式	C19H27N5O6S
分子量	453.51
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Oclacitinib maleate (formerly PF-03394197 maleate) is a novel and potent inhibitor of JAK (Janus kinase) family members with IC50 values ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM. Oclacitinib did not inhibit a panel of 38 non-JAK kinases and is the most potent at inhibiting JAK1. Oclacitinib also inhibits the function of JAK1-dependent cytokines involved in allergy and inflammation as well as pruritus. Cclacitinib is a targeted therapy that selectively inhibits JAK1-dependent cytokines involved in allergy, inflammation, and pruritus and suggests these are the mechanisms by which oclacitinib effectively controls clinical signs associated with allergic skin disease in dogs.

奥拉替尼马来酸盐 (1208319-27-0)

Oclacitinib Maleate (PF-03394197 Maleate)

化学品安全说明书(MSDS)