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达罗托组单抗

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Dalotuzumab (Anti-IGF1R / CD221)

产品编号：CLA1248 CAS No.：1005389-60-5 MDLNo： 分子式： 分子量：

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规格	库存	目录价	会员专享价	数量
1 mg	3-5days	￥3000.00	登录后可见	- +
5 mg	3-5days	￥12500.00	登录后可见	- +
10 mg	3-5days	￥20000.00	登录后可见	- +
50 mg	3-5days	￥80000.00	登录后可见	- +
100 mg	3-5days	￥125000.00	登录后可见	- +

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基本信息

英文名称	Dalotuzumab (Anti-IGF1R / CD221)
中文名称	达罗托组单抗
CAS号	1005389-60-5
储存条件	Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage. Use a manual defrost freezer and avoid repeated freeze-thaw cycles, away from light.

产品详情

Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R . Dalotuzumab acts by inhibiting IGF-1 - and IGF-2 -mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.