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替妥木单抗

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Teprotumumab (Anti-IGF-1R / CD221)

产品编号：CLA1251 CAS No.：1036734-93-6 MDLNo： 分子式： 分子量：

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规格	库存	目录价	会员专享价	数量
1 mg	3-5days	￥2000.00	登录后可见	- +
5 mg	3-5days	￥7500.00	登录后可见	- +
10 mg	3-5days	￥12000.00	登录后可见	- +
50 mg	3-5days	￥28000.00	登录后可见	- +
100 mg	3-5days	￥45600.00	登录后可见	- +

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基本信息

英文名称	Teprotumumab (Anti-IGF-1R / CD221)
中文名称	替妥木单抗
CAS号	1036734-93-6
储存条件	Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage. Use a manual defrost freezer and avoid repeated freeze-thaw cycles, away from light.

产品详情

Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab reduces TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used in the study of thyroid-associated eye diseases.