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促红细胞生成素 | EPO

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Erythropoietin | EPO | Erythropoietin-α

产品编号:CLA1658 CAS No.:11096-26-7 MDLNo: 分子式: 分子量:
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基本信息
英文名称 Erythropoietin | EPO | Erythropoietin-α
中文名称促红细胞生成素 | EPO
CAS号11096-26-7
分子式
分子量
储存条件 storage at -20 ℃.
产品详情

Recombinant, human erythropoietin (EPO) expressed in CHO cells. EPO is a glycoprotein hormone produced by the kidneys that is involved in the survival, growth, and differentiation of erythroid precursor cells. Stimulation of erythropoiesis involves the binding of EPO to the extracellular domain of the EPO receptor (EPOR) and triggering of intracellular signaling events, including phosphorylation of the receptor and activation of the JAK-STAT, RAS, and PI3-kinase pathways. Reported to act as a neuroprotective agent. Expressed in and purified from CHO cells. The predicted molecular weight is ~21 kDa, but it migrates at ~37 kDa on SDS-PAGE. Sialic acid content: > 10 moles/mole of protein. Sialic acid content: > 10 moles/mole of protein.

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