Reparixin | Repertaxin | DF 1681Y

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Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Reparixin (Synonyms: Repertaxin; DF 1681Y)
CAS	266359-83-5
Formula	C14H21NO3S
MW	283.39
Appearance	White to off-white powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC₅₀s of 1 and 100 nM, respectively.
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Related literature

Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2non-competitive allosteric inhibitor.

PMID: 21718305 PMCID: PMC3268197 DOI: 10.1111/j.1476-5381.2011.01566.x

Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2.

PMID: 17665889 DOI: 10.1021/jm061469t

Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischemic stroke in mice.

PMID: 23644861 PMCID: PMC3611745 DOI: 10.6061/clinics/2013(03)oa17