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帕马考昔 | 泊马昔布

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Catalog No：CL1161 CAS No.：301692-76-2 MDLNo： Formula：C18H16FNO4S MW：361.39

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	￥586.00	Visible after login	- +
10 mg	3-5days	￥998.00	Visible after login	- +

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Product Overview

Product Name	Polmacoxib
CAS	301692-76-2
Formula	C18H16FNO4S
MW	361.39
Appearance	Light yellow to green yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.

Related literature

CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models.

PMID: 28421763 DOI: 10.1021/acs.jmedchem.7b00010

ynthetic Approaches to the New Drugs Approved During 2015

PMID: 28421763 DOI: 10.1021/acs.jmedchem.7b00010

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CL1161

Polmacoxib

301692-76-2 98+%