Product Name | Pralsetinib (Synonyms:Pralsetinib free base; BLU-667) |
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CAS | 2097132-94-8 |
Formula | C27H32FN9O2 |
MW | 533.60 |
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Product Name | Pralsetinib (Synonyms:Pralsetinib free base; BLU-667) |
---|---|
CAS | 2097132-94-8 |
Formula | C27H32FN9O2 |
MW | 533.60 |
Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC50s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively.