Bemcentinib | R428 | BGB324 | CAS 1037624-75-1

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	In-stock	￥866.00	Visible after login	- +
10 mg	In-stock	￥1466.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

In-stock

￥866.00

Visible after login

- +

10 mg

In-stock

￥1466.00

Visible after login

- +

Product Overview

Product Name	Bemcentinib \| R428 \| BGB324
CAS	1037624-75-1
Formula	C30H34N8
MW	506.64
Appearance	Off-white to yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Bemcentinib (formerly known as BGB324; R428) is a novel, potent and selectiveinhibitor of the RTK (receptor tyrosine kinase) Axl with potential anticancer activity.

Related literature

Human cutaneous melanomas lacking MITF and melanocyte differentiation antigens express a functional Axl receptor kinase.

PMID: 21796150 DOI: 10.1038/jid.2011.218

R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.

PMID: 20145120 DOI: 10.1158/0008-5472.CAN-09-2997

Growth arrest-specific protein 6 receptor antagonism impairs adipocyte differentiation and adipose tissue development in mice.

PMID: 21285281 DOI: 10.1124/jpet.110.178046

Sorry, no related items

History

CL1245

Bemcentinib | R428 | BGB324

1037624-75-1 98+%

贝森替尼

Chemical safety data sheet(MSDS)

Certificate Of Authenticity(CPA)