Ulixertinib HCl salt | Ulixertinib hydrochloride | BVD-523 hydrochloride | 1956366-10-1

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Product Overview

Product Name	Ulixertinib hydrochloride (Synonyms: BVD-523 hydrochloride; VRT752271 hydrochloride;Ulixertinib HCl salt) ; (S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide hydrochloride.
CAS	1956366-10-1
Formula	C21H23Cl3N4O2
MW	469.79
MDL	MFCD22543853

Product details

Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.

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