Home > Category > Signaling Pathways > Antibody-drug Conjugate/ADC Related > Drug-Linker Conjugates for ADC > VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Mc-Val-Cit-PAB-MMAE

4-((S)-2-((S)-2-(6-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)己酰胺)-3-甲基丁酰胺)-5-脲基戊酰胺)苄基((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-羟基-1-苯丙烷-2-基)氨基)-1-甲氧基-2-甲基-3-氧代丙基）吡咯烷-1-基)-3-甲氧基-5-甲基-1-氧代庚-4-基)(甲基)氨基)-3-甲基-1-氧代丁烷-2-基)氨基)-3-甲基-1-氧代丁烷-2-基)(甲基)氨基甲酸酯

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Catalog No：CL1347 CAS No.：646502-53-6 MDLNo： Formula：C68H105N11O15 MW：1,316.63

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Product Overview

Product Name	VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Mc-Val-Cit-PAB-MMAE
CAS	646502-53-6
Formula	C68H105N11O15
MW	1,316.63
Storage condition	Avoid light, nitrogen, -20 ℃

Product details

VcMMAE (mc-vc-PAB-MMAE), a MMAE derivative with valine-citrulline (Vc) linker,is an Drug-linker Conjugate for antibody-drug conjugate (ADC) with potent antitumor activity. MMAE is a synthetic antineoplastic agent and can be efficiently released from VcMMAE in vitro and exert cytotoxic activity.

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CL1347

VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Mc-Val-Cit-PAB-MMAE

646502-53-6 98+%