Nirmatrelvir | PF-07321332 |CAS 2628280-40-8 | SARS-CoV inhibitor

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	In-stock	￥306.00	Visible after login	- +
2 mg	In-stock	￥486.00	Visible after login	- +
5 mg	In-stock	￥876.00	Visible after login	- +
10 mg	In-stock	￥1566.00	Visible after login	- +
25 mg	In-stock	￥2766.00	Visible after login	- +
50 mg	In-stock	￥3898.00	Visible after login	- +
100 mg	In-stock	￥5466.00	Visible after login	- +
250 mg	In-stock	￥7688.00	Visible after login	- +
500 mg	In-stock	￥10368.00	Visible after login	- +
1 g	In-stock	￥18562.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

In-stock

￥306.00

Visible after login

- +

2 mg

In-stock

￥486.00

Visible after login

- +

5 mg

In-stock

￥876.00

Visible after login

- +

10 mg

In-stock

￥1566.00

Visible after login

- +

25 mg

In-stock

￥2766.00

Visible after login

- +

50 mg

In-stock

￥3898.00

Visible after login

- +

100 mg

In-stock

￥5466.00

Visible after login

- +

250 mg

In-stock

￥7688.00

Visible after login

- +

500 mg

In-stock

￥10368.00

Visible after login

- +

1 g

In-stock

￥18562.00

Visible after login

- +

Product Overview

Product Name	Nirmatrelvir (Synonyms: PF-07321332)
CAS	2628280-40-8
Formula	C23H32F3N5O4
MW	499.53
MDL	MFCD34473213
Appearance	White powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Nirmatrelvir (PF-07321332) is a SARS-CoV 3CLPRO inhibitor, a trypsin-like protease inhibitor with potent and oral activity. Nirmatrelvir is targeted against SARS-CoV-2 viruses and can be studied in COVID-19.
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Related literature

Considerations for the Discovery and Development of 3-Chymotrypsin-Like Cysteine Protease Inhibitors Targeting SARS-CoV-2 Infection.

https://doi.org/10.1016/j.coviro.2021.04.006

Nirmatrelvir exerts distinct antiviral potency against different human coronaviruses.

PMID: 36791846 PMCID: PMC9925195 DOI: 10.1016/j.antiviral.2023.105555

SARS-CoV-2 Omicron variant is highly sensitive to molnupiravir, nirmatrelvir, and the combination.

PMID: 35058606 PMCID: PMC8771185 DOI: 10.1038/s41422-022-00618-w

Combination therapy with nirmatrelvir and molnupiravir improves the survival of SARS-CoV-2 infected mice. Antiviral Res.

PMID: 36209984 PMCID: PMC9535923 DOI: 10.1016/j.antiviral.2022.105430

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History

CL1431

Nirmatrelvir (Synonyms: PF-07321332)

2628280-40-8 Purity: 99.26%

(1R,2S,5S)-N-((S)-1-氰基2-((S)-2-氧代吡咯烷-3-基)乙基)-3-((S)-3,3-二甲基-2-(2,2,2-三氟乙酰胺基)丁酰基)-6,6-二甲基-3-氮杂双环[3.1.0]己烷-2-甲酰胺; 奈玛特韦

Chemical safety data sheet(MSDS)

Certificate Of Authenticity(CPA)