Home > Category > Signaling Pathways > Protein Tyrosine Kinase/RTK > Anaplastic lymphoma kinase (ALK) > Alectinib Hydrochloride (Synonyms: CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride;Alectinib HCl)

9-乙基-6,6-二甲基-8-(4-吗啉-4-基哌啶-1-基)-11-氧代-5H-苯并[b]咔唑-3-腈盐酸盐;艾乐替尼盐酸盐;盐酸阿来替尼

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Catalog No：CL1457A CAS No.：1256589-74-8 MDLNo：MFCD27987893 Formula：C30H35ClN4O2 MW：519.08

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Product Overview

Product Name	Alectinib Hydrochloride (Synonyms: CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride;Alectinib HCl)
CAS	1256589-74-8
Formula	C30H35ClN4O2
MW	519.08
MDL	MFCD27987893

Product details

Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

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CL1457A

Alectinib Hydrochloride (Synonyms: CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride;Alectinib HCl)

1256589-74-8 99+%