Product Name | Entecavir Monohydrate |
---|---|
CAS | 209216-23-9 |
Formula | C12H17N5O4 |
MW | 295.29 |
MDL | MFCD09754448 |
Appearance | White to off-white powder |
Storage condition | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. |
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Product Name | Entecavir Monohydrate |
---|---|
CAS | 209216-23-9 |
Formula | C12H17N5O4 |
MW | 295.29 |
MDL | MFCD09754448 |
Appearance | White to off-white powder |
Storage condition | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. |
Entecavir monohydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of hepatitis B virus (HBV), exhibiting an EC50 of 3.75 nM in HepG2 cells. This compound is recognized for its high potency and specificity in inhibiting HBV replication, making it a valuable asset in the research and treatment of chronic hepatitis B.
A review of entecavir in the treatment of chronic hepatitis B infection.
PMID: 16307706 DOI: 10.1185/030079905X65268
PMID: 9835516 PMCID: PMC106024 DOI: 10.1128/AAC.42.12.3209
Identification of?BMS-200475?as a potent and selective inhibitor of hepatitis B virus.
PMID: 9210663 PMCID: PMC163937 DOI: 10.1128/AAC.41.7.1444