Cediranib | ADZ-2171 | NSC-732208

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Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Cediranib \| ADZ-2171 \| NSC-732208
CAS	288383-20-0
Formula	C25H27FN4O3
MW	450.51
Appearance	White to yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Cediranib (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC₅₀s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.

Related literature

AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer.

PMID: 15899831 DOI: 10.1158/0008-5472.CAN-04-4409

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

PMID: 26645582 DOI: 10.1126/scisignal.aaa1690

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History

CL1631

Cediranib | ADZ-2171 | NSC-732208

288383-20-0 98+%

西地尼布

Chemical safety data sheet(MSDS)