Product Name | Etoricoxib (MK-663; MK-0663) |
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CAS | 202409-33-4 |
Formula | C18H15ClN2O2S |
MW | 358.84 |
Appearance | Light yellow to yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
25 mg | 3-5days | ¥400.00 | Visible after login | |
50 mg | 3-5days | ¥650.00 | Visible after login | |
100 mg | 3-5days | ¥850.00 | Visible after login |
Product Name | Etoricoxib (MK-663; MK-0663) |
---|---|
CAS | 202409-33-4 |
Formula | C18H15ClN2O2S |
MW | 358.84 |
Appearance | Light yellow to yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Etoricoxib (also known as MK-0663) is a non-steroidal anti-inflammatory drgu (NSAID) which acts as a selective and orally bioactive COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. Etoricoxib is a synthetic NSAID with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib binds specifically to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.