SP600125 | Nsc75890 | SP 600125 | Anthra[1,9-cd]pyrazol-6(2H)-one | 1,9-Pyrazoloanthrone

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Product Overview

Product Name	SP600125 (Synonyms: Nsc75890; SP 600125; Anthra[1,9-cd]pyrazol-6(2H)-one;1,9-Pyrazoloanthrone; Anthrapyrazolone)
CAS	129-56-6
Formula	C14H8N2O
MW	220.23
MDL	MFCD00022289

Product details

SP600125 is an orally active, reversible, and ATP-competitive JNK inhibitor with IC50s of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. SP600125 is a potent ferroptosis inhibitor. SP600125 induces the transformation of bladder cancer cells from autophagy to apoptosis.

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