| Product Name | Timapiprant Sodium (Synonyms: OC000459 Sodium) | 
|---|---|
| CAS | 950688-14-9 | 
| Formula | C21H16FN2NaO2 | 
| MW | 370.35 | 
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| Product Name | Timapiprant Sodium (Synonyms: OC000459 Sodium) | 
|---|---|
| CAS | 950688-14-9 | 
| Formula | C21H16FN2NaO2 | 
| MW | 370.35 | 
Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils.