Pictilisib | GDC-0941 | RG7321

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Pictilisib \| GDC-0941 \| RG7321
CAS	957054-30-7
Formula	C23H27N7O3S2
MW	513.64
Appearance	White to yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

It is currently being investigated for its potential in treating various types of cancer, including solid tumors, breast cancer, and non-Hodgkin’s lymphoma. Pictilisib works by targeting the PI3K pathway, which is often deregulated in cancer cells, leading to uncontrolled cell growth and survival.

Related literature

A genetic mouse model of invasive endometrial cancer driven by concurrent loss of Pten and Lkb1 Is highly responsive to mTOR inhibition.

PMID: 24322983 PMCID: PMC3982380 DOI: 10.1158/0008-5472.CAN-13-0544

Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent.

PMID: 22588880 PMCID: PMC3384541 DOI: 10.1158/2159-8290.CD-12-0003

GDC-0941 inhibits metastatic characteristics of thyroid carcinomas by targeting both the phosphoinositide-3 kinase (PI3K) and hypoxia-inducible factor-1α (HIF-1α) pathways

PMID: 21994956 DOI: 10.1210/jc.2011-1426

Sorry, no related items

History

CL2026

Pictilisib | GDC-0941 | RG7321

957054-30-7 98+%

匹替利司 | 2-(1H-吲唑-4-基)-6-[[4-(甲基磺酰基)-1-哌嗪基]甲基]-4-(4-吗啉基)噻吩并[3,2-d]嘧啶; 匹替利司

Chemical safety data sheet(MSDS)