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6-[[6-(1-甲基-1H-吡唑-4-基)-1,2,4-三唑并[4,3-b]哒嗪-3-基]硫基]喹啉

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Catalog No：CL2357 CAS No.：1022150-57-7 MDLNo： Formula：C18H13N7S MW：359.41

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
2 mg	In-stock	￥288.00	Visible after login	- +
5 mg	In-stock	￥466.00	Visible after login	- +
10 mg	In-stock	￥746.00	Visible after login	- +

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Product Overview

Product Name	SGX-523
CAS	1022150-57-7
Formula	C18H13N7S
MW	359.41
Appearance	Light yellow to yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

SGX523 is an exquisitely selective and ATP-competitive MET inhibitor. SGX523 potently inhibits MET with an IC₅₀ of 4 nM and is >1,000-fold selective versus other protein kinases. Antitumor activity.

Related literature

SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.

PMID: 19934279 DOI: 10.1158/1535-7163.MCT-09-0477

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CL2357

SGX-523

1022150-57-7 98+%